The intensity of effects from 2CB increases steadily along with the dose. All 2C- substances contain methoxy groups on the 2 and 5 positions of a benzene ring of its chemical structure. Take a lower dose than you normally would and give it time to take effect. Peak effects last between 1 and 2 hours before tapering off. The best way to avoid a 2C-B hangover is to drink plenty of water throughout the experience and ensure you’re getting a full 8 hours of sleep afterward.
What to Do During a Bad Trip or Overdose
Some could even describe the visuals at higher doses to be “cartoon-like” — which is similar to the visuals experienced with higher doses of mescaline. 2C-B does not produce cross-tolerance with other serotonergic psychedelics, although most users report other psychedelics affecting 2C-B tolerance. Users have reported experiencing hypertension, hyperthermia and tachycardia at higher doses. In other words, users should avoid a dose that large in order to avoid long term damage, but typical doses should be well within a safe range. Anecdotal evidence suggests that there are no negative health effects attributed to simply trying it by itself at low to moderate doses or using it very sparingly (although nothing can be completely guaranteed).
-B and mental health
Similar to other psychedelics, 2C-B does not produce dependence. This is consistent with what the evidence tells us about people with mental illness and psychedelic use.6 According to anecdotal user reports, the after-effects or comedown of taking 2C-B can last for around 2-4 hours.3 For example, feelings of stress or anxiety before using 2C-B may result in an unpleasant experience (bad trip).5
A 2015 study in Spain suggested that the drug reduced aggression and encouraged open-mindedness, but the results were inconclusive. Some insufflate or vaporize the substance, though this is rare. Occasionally, people snort it, though doing so often causes nosebleeds and is potentially lethal. Anecdotal reports claim that the drug typically appears as a white powder or crystal. Although popular for its recreational effects, 2C-B use can lead to addiction and other long-term consequences.
2C-B is metabolized by the monoamine oxidases (MAOs) A and B, so it likely poses a risk for people on MAO inhibitors (MAOIs). Our in depth guide and step-by-step videos will have you harvesting your own home-grown mushrooms in no time. In Third Wave’s Ultimate Guide to Safely Sourcing Psychedelics, you will discover an astonishing menu of psychedelic medicines……and how to source them without legal risk. Further activation of α1-adrenergic receptors may be responsible for 2C-B’s stimulant effects.
Hallucinogens & Psychedelics
- 2C-B has stimulating effects that could be dangerous for people with heart disease or who are taking heart medications.
- People diagnosed with a mental illness are more significantly at risk of its adverse effects.
- Samples of 2C-B have been shown to contain substances such as methamphetamines, MDA, PMA, PMMA, NBOMe, or various opiates.
- “Plugging” liquid 2C-B into the rectum with a needleless syringe has similar effects, even on a full stomach.
- 5) The drug will kick in faster and your trip may last for longer.
It is a synthetic analogue of the naturally occurring phenethylamine psychedelic mescaline found in peyote and certain other cacti. In another study, with 20 mg 2C-B orally, peak levels were 3.31 ng/mL and time to peak levels was 2.43 hours. With 30 mg 2C-B by orally, its peak concentrations (mean ± SD) were 5.4 ng/mL and its time to peak concentrations was 2.3 hours. 2C-B produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents. 2C-B has been reported to be an allosteric or non-competitive serotonin transporter (SERT) inhibitor or serotonin reuptake inhibitor, albeit of very low potency. It was reported by Alexander 2cb effects Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) that a psychologist had accidentally taken a 100 mg dose orally without apparent harm.
Others have reported crisper vision, enhanced tactile awareness, and a mental energy boost comparable to caffeine. “Plugging” liquid 2C-B into the rectum with a needleless syringe has similar effects, even on a full stomach. Vaporizing freebase 2C-B in a glass pipe is reportedly more potent and faster-acting than oral use, but with a shorter total duration.
To minimize negative experiences on 2C-B, always keep in mind the 6Ss of psychedelic use and prepare appropriately. Nevertheless, the few cases of long-term psychosis attributed to 2C-B are highly questionable, and it’s not known that the drug was even involved. At very high doses, some have questioned their sanity. While it could potentially trigger a false positive for amphetamines, this is unlikely given the small doses involved. Although 2C-B has sometimes been sold as MDMA, the effects are substantially different. 2C-B also appears to be one of the most commonly sourced substances on the darknet.
- This article provides information on the various aspects of 2C-B, including its effects, potential risks, legal status, and much more.
- Dosage is another important factor, as increments of just 2 mg can disproportionately affect the experience.
- The effects of 2C-B typically last from four to eight hours.
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2C-B is often compared to LSD because the visual effects of these two drugs are very similar. Never attempt to eyeball your dose of 2C-B of any powdered drugs. Of our respondents, only 7% reported any negative impact the following morning after using doses lower than 35 mg of 2C-B.
What does 2C-B feel like?
Shulgin suggested snorting the more water-soluble acetate or hydrobromide salt for the same effects with little to no pain. Other methods include snorting, vaporizing, and “plugging” (rectal administration). One user even reported an alarming fear of anything alive—even plants. Despairing thoughts, paranoid delusions, and frightening visuals (like facial distortions) may occur during a 2C-B trip.
Other related cyclized compounds, while not technically phenethylamines or 2C-B derivatives, include 2C-B-BZP and 2C-B-PP. Another N-substituted derivative, 2C-B-AN, is an N-benzylphenethylamine-like prodrug of 2C-B. This initial research did not include functional assays of activity, but later led to the development of potent substituted N-benzyl derivatives such as 25B-NBOMe, and 25B-NBOH. Βk-2C-B shows dramatically reduced potency and efficacy as a serotonin 5-HT2A receptor agonist compared to 2C-B. Analogues of 2C-B include 2C-I, 2C-C, DOB, 4C-B, 2C-B-FLY, and 25B-NBOMe, among others.
Analogues and derivatives
The drug was discovered in 1974 and has since then become one of the most popular psychedelics in the world. The effects of taking 2C-B with other drugs − including over-the-counter or prescribed medications − can be unpredictable and dangerous. There have been no reported deaths from 2C-B, but deaths have occurred from the use of other 2C drugs.2 Set is a person’s state of mind, previous encounters with psychedelic drugs, and expectations of what’s going to happen. 2C-B (4-Bromo-2,5-dimethoxyphenethylamine) is a psychedelic drug, which means it can affect all the senses, altering a person’s thinking, sense of time and emotions.
-P: The Strongest Member of the 2C Family of Psychedelics
Common side effects can include nausea, confusion, paranoia, and anxiety. The drug is commonly used as a party drug as it provides stimulant effects similar to cocaine as well as hallucinatory effects similar to MDMA. The way 2C-B interacts with the brain and its ability to mimic serotonin reactions have also led to the drug being likened to antidepressants. 2C drugs come in multiple forms including 2C-E, 2C-I, 2CT-7, and 2CB which is the most commonly used version available today. 2C drugs – such as 2CB, 2CI, and 2CE – are designer drugs that have both hallucinogenic and stimulant properties. Unlike 2C-B, 2C-P has a history of overdoses dating back to the early-90s – although Fletcher-Michie was the first recorded death – and today is sold by just one darknet dealer.
2C-B was first encountered as a novel recreational designer drug in the United States in 1985. Shulgin proposed 2C-B and 2C-D for use in psychedelic-assisted psychotherapy. He described the properties and effects of 2C-B in humans, along with those of 2C-D, in the scientific literature in 1975.
(Nexus, Venus, Bromo mescaline, Bees, Toonies)
Yes, 2C-B is a strong psychedelic — especially in higher doses. Sometimes 2C-B can feel a little bit “speedy” or “tweaky” — especially in the higher doses. In smaller doses these effects are limited, but higher doses of 2C-B produce intense changes in sensory perception. This is a dose nearly three times what’s considered a high dose for the substance. 2C-B (4-bromo-2,5-dimethoxyphenethylamine) is a synthetic psychedelic substance derived from mescaline. The Drop is BDP’s one stop shop for support, advice and resources around party drugs.